{"id":7521,"date":"2026-06-24T02:15:02","date_gmt":"2026-06-24T02:15:02","guid":{"rendered":"https:\/\/vitromasterdiagnostica.bio\/microbiology-reagents\/microbiology-reagents-dna-flow-meningitis\/"},"modified":"2026-09-20T11:34:52","modified_gmt":"2026-09-20T11:34:52","slug":"microbiology-reagents-dna-flow-meningitis","status":"publish","type":"page","link":"https:\/\/vitromasterdiagnostica.bio\/en\/microbiology-reagent\/microbiology-reagents-dna-flow-meningitis\/","title":{"rendered":"MICROBIOLOGY – REAGENTS – DNA FLOW – MENINGITIS"},"content":{"rendered":"\t\t
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Detection of bacteria causing meningitis \/ encephalitis in humans using multiplex PCR and reverse hybridisation.\n<\/h1>\t\t\t\t<\/div>\n\t\t\t\t
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In vitro diagnostic kit for bacteria and fungi causing meningitis and encephalitis in humans using DNA Flow technology, providing reliable results for clinical laboratories and molecular microbiology.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Multiplex
Detection\n\n\n\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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Simultaneous detection of 9 bacteria and 1 fungus associated with meningitis and encephalitis in CSF using multiplex PCR and DNA-Flow reverse hybridisation.\n\n\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Clinically
Relevant Panel\n\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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Includes N. meningitidis, S. pneumoniae, S. agalactiae, L. monocytogenes, H. influenzae, M. tuberculosis complex, T. pallidum, C. burnetii, B. burgdorferi and C. neoformans.\n\n\n\n\n\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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High Sensitivity
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\n\t\t\t\t\tDetection limits verified from 10 copies\/reaction for various targets, with 100% analytical specificity and no cross-reactions between the included organisms.\n\n\n\n\n\n<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Automation and
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\n\t\t\t\t\tCompatible with Vitro hybriSpot platforms, including HS12, HS24 and HS12 PCR AUTO, with automatic result analysis via hybriSoft.\n\n\n\n<\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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DNA Flow<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t
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Bacterial CNS Flow Chip Kit <\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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Detection of bacteria causing meningitis\/encephalitis in humans using multiplex PCR and reverse hybridisation.MAD-003935M-HS12-24 – 24 determinationsMAD-003935M-HS24-24 – 24 determinations<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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Kit Information<\/strong>The Bacterial CNS Flow Chip kit is an in vitro diagnostic kit for bacteria and fungi causing meningitis and encephalitis in humans. Current diagnostic methods are very laborious and do not always show 100% specificity. The Bacterial CNS Flow Chip system allows for the simultaneous detection of nine bacterial species (Neisseria meningitidis, Streptococcus pneumoniae, Streptococcus agalactiae, Listeria monocytogenes, Haemophilus influenzae, Mycobacterium tuberculosis complex, Treponema pallidum, Coxiella burnetii, and Borrelia burgdorferi) and one fungus (Cryptococcus neoformans) through bacterial DNA amplification by multiplex PCR and subsequent reverse hybridisation on a membrane containing specific DNA probes for each species. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Rapid molecular diagnosis for <\/span> bacterial meningitis\/encephalitis<\/span><\/h2>
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Bacterial meningitis continues to be a major public health problem, with over a million cases and more than 200,000 deaths annually worldwide. Rapid diagnosis is crucial for initiating appropriate treatment and improving patient prognosis. <\/p>

Bacterial<\/b> CNS Flow Chip<\/b> enables the simultaneous detection of nine meningitis-causing bacteria using molecular hybridisation technology, providing a rapid, accurate, and highly sensitive diagnosis for clinical laboratories.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Benefits of <\/span> DNA FLOW TECHNOLOGY<\/span><\/h2>
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Advanced Multiplexing\n\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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Sensitive and specific simultaneous identification of genetic material from different pathogenic microorganisms and antibiotic resistance markers in a single assay.\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Diagnostic flexibility\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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Our reagents allow for the analysis of a wide spectrum of sample types, from blood to urine, swabs, liquid cytology, sputum, bronchial washes, among others. Applicable to different diagnostic areas. \n\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Fast and Accurate Results\n\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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Consolidated automated reverse hybridisation technology on a porous membrane microarray containing specific oligonucleotides for each marker.<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Safety and traceability\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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Complete sample control and bidirectional connectivity with LIS for secure and efficient diagnostic process management. Automated interpretation and full traceability via hybriSoft. \n\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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MANAGEMENT SOFTWARE\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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TRACEABILITY AND ANALYSIS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Software designed to automate processes, ensure traceability, analyse results and connect with the LIS in a fully integrated workflow.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\n\t\t\t\t\t\t\t\t\tAdvanced management system for HybriSpot equipment, allowing for sample management, image capture and automated analysis and interpretation of results, with a bidirectional connection to the LIS.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Technology for<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Molecular Diagnosis<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Specialised platforms for extraction, real-time PCR, reverse hybridisation, and traceability designed to improve laboratory diagnostic efficiency and reliability.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\"Vitrocycler\"<\/figure>

VitroCycler<\/h3>

Real-time PCR platform.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t

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\"Hycrystpot\"<\/figure>

Hybrispot<\/h3>

PCR and reverse hybridisation system for molecular detection.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t

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\"Mais\"<\/figure>

MAIS<\/h3>

MAIS Comprehensive molecular solution with full automation.\n<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t

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\"Victoria\"<\/figure>

MAIS Victoria V96<\/h3>

Fully automated instrument for the pre-analytical and analytical phases.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t

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ARE YOU LOOKING FOR A COMPREHENSIVE SOLUTION FOR<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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YOUR DIAGNOSTIC LABORATORY?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Our specialised team helps you identify the most suitable technology, reagents, and instrumentation to optimise your diagnostic processes.<\/p>

With Vitro’s Molecular Microbiology solutions, we improve laboratory automation, traceability, and efficiency, from sample to final result.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Detection of bacteria causing meningitis \/ encephalitis in humans using multiplex PCR and reverse hybridisation. In vitro diagnostic kit for […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":7453,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"iawp_total_views":0,"footnotes":""},"class_list":["post-7521","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/vitromasterdiagnostica.bio\/en\/wp-json\/wp\/v2\/pages\/7521","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vitromasterdiagnostica.bio\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/vitromasterdiagnostica.bio\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/vitromasterdiagnostica.bio\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vitromasterdiagnostica.bio\/en\/wp-json\/wp\/v2\/comments?post=7521"}],"version-history":[{"count":7,"href":"https:\/\/vitromasterdiagnostica.bio\/en\/wp-json\/wp\/v2\/pages\/7521\/revisions"}],"predecessor-version":[{"id":8428,"href":"https:\/\/vitromasterdiagnostica.bio\/en\/wp-json\/wp\/v2\/pages\/7521\/revisions\/8428"}],"up":[{"embeddable":true,"href":"https:\/\/vitromasterdiagnostica.bio\/en\/wp-json\/wp\/v2\/pages\/7453"}],"wp:attachment":[{"href":"https:\/\/vitromasterdiagnostica.bio\/en\/wp-json\/wp\/v2\/media?parent=7521"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}